Best Female Lead movies of 2000s

Actors : Jo Prestia, Vincent Cassel, Monica Bellucci, Albert Dupontel,
Directors : Gaspar Noé,

Events over the course of one traumatic night in Paris unfold in reverse-chronological order as the beautiful Alex is brutally raped and beaten by a stranger in the underpass.

Actors : Marc Barbé, Delphine Chuillot, Marie Féret, David Moreau,
Directors : René Féret,

A reimagined account of the early life of Maria Anna 'Nannerl' Mozart, five years older than Wolfgang, and a musical prodigy in her own right.

Actors : Karel Roden, Anastasia Hille, Valentin Goshev, Valentin Ganev,
Directors : Nacho Cerdà,

An adopted woman returns to her home country and the family home that she never knew and must face the mystery that lies there.

Actors : Alicia Fulford-Wierzbicki, Sarah Peirse, Marton Csokas, Alistair Browning,
Directors : Christine Jeffs,

Whilst on a family vacation on the Mahurangi Peninsula in New Zealand, 13-year-old Janey begins to realize that her parents' marriage is on the rocks.

Actors : Frances Conroy, Julianne Moore, Jonathan Rhys Meyers, Jeffrey DeMunn,

A female forensic psychiatrist discovers that all of one of her patient's multiple personalities are murder victims. She will have to find out what's happening before her time is finished.

Actors : Dori Mizrahi, Michael Ealy, Courteney Cox, James Le Gros,
Directors : Greg Harrison,

Sophie Jacobs is going through the most difficult time of her life. Now, she just has to find out if it's real.

Actors : Joy Bryant, Gena Rowlands, Peter Sarsgaard, Kate Hudson,
Directors : Iain Softley,

A hospice nurse working at a spooky New Orleans plantation home finds herself entangled in a mystery involving the house's dark past.

Actors : Derya Alabora, Nizam Schiller, Sibel Kekilli, Settar Tanriögen,
Directors : Feo Aladag,

Umay is a young woman of Turkish descent, fighting for an independent and self-determined life in Germany against the resistance of her family. Her struggle initiates a dynamic, which results in a life-threatening situation.

Actors : Alfre Woodard, Sanaa Lathan, Rockmond Dunbar, Kathy Bates,
Directors : Tyler Perry,

Two families from different walks of life learn to work together.

Actors : Samuel L. Jackson, Justin Timberlake, Christina Ricci, S. Epatha Merkerson,
Directors : Craig Brewer,

A God-fearing bluesman takes to a wild young woman who, as a victim of childhood sexual abuse, looks everywhere for love, never quite finding it.

Actors : Anna Paquin, Giancarlo Giannini, Lena Olin, Iain Glen,
Directors : Jaume Balagueró,

A teenage girl moves into a remote countryside house with her family, only to discover that their gloomy new home has a horrifying past that threatens to destroy the family.

Actors : Fumiko Orikasa, Shôzô Îzuka, Miyoko Shôji, Mami Koyama,
Directors : Satoshi Kon,

A TV interviewer and his cameraman meet a former actress and travel through her memories and career.

Actors : Jimmy Jean-Louis, Godfrey, Mo'Nique, Kendra C. Johnson,
Directors : Nnegest Likké,

Two plus-sized ladies meet the men of their dreams in the most unexpected of ways.

Actors : Dina Korzun, Darren E. Burrows, Andrew Lawrence Henderson, Rip Torn,
Directors : Ira Sachs,

A Russian woman living in Memphis with a much older rock-'n'-roll legend experiences a personal awakening when her husband's estranged son comes to visit.

Actors : Rosemarie Bergmans, Julienne De Bruyn, Dora van der Groen, Ann Petersen,
Directors : Lieven Debrauwer,

Pauline is a 'little girl of 66 years old'. She is intellectually disabled and been cared after by her sister Martha. When Martha dies, her two younger sisters, Paulette and Cecile have to ...

Actors : Soraya Omar-Scego, Idriss Abdillahi Houfaneh, Awa Saïd Darar, Roun Daher Aïnan,
Directors : Sherry Hormann,

The autobiography of a Somalian nomad circumcised at 3, sold in marriage at 13, fled from Africa a while later to become finally an American supermodel and is now at the age of 38, the UN ...

Actors : Jennifer Syme, Greg Freitas, Gaye Pope, Naomi Watts,
Directors : Scott Coffey,

A hilarious comic portrait of a young woman's struggle for integrity, happiness and a Hollywood acting career.

Actors : Sami Bouajila, Sotigui Kouyaté, Brenda Blethyn, Roschdy Zem,
Directors : Rachid Bouchareb,

Two strangers come to discover the fate of their respective children in the 2005 terrorist attacks on London.

Actors : Micaela Nevárez, Mariana Cordero, Llum Barrera, Candela Peña,
Directors : Fernando León de Aranoa,

Friendship and love in the world of prostitution in Madrid.

Actors : Grégoire Colin, Anne Parillaud, Ashley Wanninger, Roxane Mesquida,
Directors : Catherine Breillat,

A director struggles to film a difficult, intimate sex scene between two actors who happen to hate each other.