Best Female Lead movies of 2000s

Actors : Jaya Bhaduri, Saif Ali Khan, Shah Rukh Khan, Preity Zinta,
Directors : Nikkhil Advani,

Naina, an introverted, perpetually depressed girl's life changes when she meets Aman. But Aman has a secret of his own which changes their lives forever. Embroiled in all this is Rohit, Naina's best friend who conceals his love for her.

Actors : Jo Prestia, Vincent Cassel, Monica Bellucci, Albert Dupontel,
Directors : Gaspar Noé,

Events over the course of one traumatic night in Paris unfold in reverse-chronological order as the beautiful Alex is brutally raped and beaten by a stranger in the underpass.

Actors : Alicia Fulford-Wierzbicki, Sarah Peirse, Marton Csokas, Alistair Browning,
Directors : Christine Jeffs,

Whilst on a family vacation on the Mahurangi Peninsula in New Zealand, 13-year-old Janey begins to realize that her parents' marriage is on the rocks.

Actors : Katie Holmes, Guy Pearce, Bailee Madison, Bruce Gleeson,
Directors : Troy Nixey,

A young girl sent to live with her father and his new girlfriend believes that she has released creatures from a sealed ash pit in the basement of her new home.

Actors : Frances Conroy, Julianne Moore, Jonathan Rhys Meyers, Jeffrey DeMunn,

A female forensic psychiatrist discovers that all of one of her patient's multiple personalities are murder victims. She will have to find out what's happening before her time is finished.

Actors : Rip Torn, Darren E. Burrows, Dina Korzun, Andrew Lawrence Henderson,
Directors : Ira Sachs,

A Russian woman living in Memphis with a much older rock-'n'-roll legend experiences a personal awakening when her husband's estranged son comes to visit.

Actors : Michael Ealy, Courteney Cox, Dori Mizrahi, James Le Gros,
Directors : Greg Harrison,

Sophie Jacobs is going through the most difficult time of her life. Now, she just has to find out if it's real.

Actors : Kendra C. Johnson, Jimmy Jean-Louis, Godfrey, Mo'Nique,
Directors : Nnegest Likké,

Two plus-sized ladies meet the men of their dreams in the most unexpected of ways.

Actors : Rosemarie Bergmans, Julienne De Bruyn, Dora van der Groen, Ann Petersen,
Directors : Lieven Debrauwer,

Pauline is a 'little girl of 66 years old'. She is intellectually disabled and been cared after by her sister Martha. When Martha dies, her two younger sisters, Paulette and Cecile have to ...

Actors : Anna Paquin, Giancarlo Giannini, Lena Olin, Iain Glen,
Directors : Jaume Balagueró,

A teenage girl moves into a remote countryside house with her family, only to discover that their gloomy new home has a horrifying past that threatens to destroy the family.

Actors : Joy Bryant, Gena Rowlands, Peter Sarsgaard, Kate Hudson,
Directors : Iain Softley,

A hospice nurse working at a spooky New Orleans plantation home finds herself entangled in a mystery involving the house's dark past.

Actors : Kathy Bates, Alfre Woodard, Sanaa Lathan, Rockmond Dunbar,
Directors : Tyler Perry,

Two families from different walks of life learn to work together.

Actors : Sibel Kekilli, Settar Tanriögen, Derya Alabora, Nizam Schiller,
Directors : Feo Aladag,

Umay is a young woman of Turkish descent, fighting for an independent and self-determined life in Germany against the resistance of her family. Her struggle initiates a dynamic, which results in a life-threatening situation.

Actors : Fumiko Orikasa, Shôzô Îzuka, Miyoko Shôji, Mami Koyama,
Directors : Satoshi Kon,

A TV interviewer and his cameraman meet a former actress and travel through her memories and career.

Actors : Samuel L. Jackson, Justin Timberlake, Christina Ricci, S. Epatha Merkerson,
Directors : Craig Brewer,

A God-fearing bluesman takes to a wild young woman who, as a victim of childhood sexual abuse, looks everywhere for love, never quite finding it.

Actors : Sami Bouajila, Sotigui Kouyaté, Roschdy Zem, Brenda Blethyn,
Directors : Rachid Bouchareb,

Two strangers come to discover the fate of their respective children in the 2005 terrorist attacks on London.

Actors : Jennifer Syme, Greg Freitas, Gaye Pope, Naomi Watts,
Directors : Scott Coffey,

A hilarious comic portrait of a young woman's struggle for integrity, happiness and a Hollywood acting career.

Actors : Soraya Omar-Scego, Idriss Abdillahi Houfaneh, Awa Saïd Darar, Roun Daher Aïnan,
Directors : Sherry Hormann,

The autobiography of a Somalian nomad circumcised at 3, sold in marriage at 13, fled from Africa a while later to become finally an American supermodel and is now at the age of 38, the UN ...

Actors : Aitana Sánchez-Gijón, Giorgio Careccia, Dino Abbrescia, Riccardo Zinna,
Directors : Gabriele Salvatores,

A young boy accidentally discovers a deep hole in the ground, where another boy is kept prisoner.

Actors : Grégoire Colin, Anne Parillaud, Ashley Wanninger, Roxane Mesquida,
Directors : Catherine Breillat,

A director struggles to film a difficult, intimate sex scene between two actors who happen to hate each other.