Best Female Lead movies of 2000s

Actors : Cicely Tyson, Jeff Daniels, AnnaSophia Robb, Eva Marie Saint,
Directors : Wayne Wang,

A mischievous dog befriends a lonely young girl in a new town and helps her make new friends.

Actors : Benno Fürmann, Franka Potente, Anna Loos, Sebastian Blomberg,
Directors : Stefan Ruzowitzky,

Medical student Paula Henning wins a place at an exclusive Heidelberg medical school. When the body of a young man she met on the train turns up on her dissection table, she begins to ...

Actors : Claudia Gerini, Natalia Barcelò, Sergio Castellitto, Penélope Cruz,
Directors : Sergio Castellitto,

A destitute woman (Cruz) becomes involved with an upper-crust physician (Castellitto).

Actors : Mya, Portia de Rossi, Christina Ricci, Jesse Eisenberg,
Directors : Wes Craven,

A werewolf loose in Los Angeles changes the lives of three young adults who, after being mauled by the beast, learn they must kill it in order to avoid becoming werewolves themselves.

Actors : Jamie Starr, Lukas Haas, Kim Basinger, Craig Sheffer,
Directors : Susan Montford,

Della Myers is an overwhelmed upper-middle-class housewife who lives in a large house in the suburbs with her twin children and her abusive husband, Kenneth. Kenneth lets Della know that he...

Actors : Maria Hofstätter, Christine Jirku, Viktor Hennemann, Georg Friedrich,
Directors : Ulrich Seidl,

In a suburb of Vienna during some hot summer days: A teacher who is in bondage to a sleazy pimp, a very importunate hitchhiker, a private detective on the run for some car vandals, a couple...

Actors : Anne Brochet, Fabrice Luchini, Sandrine Bonnaire, Michel Duchaussoy,
Directors : Patrice Leconte,

A Frenchwoman tells her marital troubles to a man she mistakes for a psychiatrist, and soon they form an unusual relationship.

Actors : Stockard Channing, Jean-Marie Lhomme, Naomi Watts, Kate Hudson,
Directors : James Ivory,

French vs. American social customs and behaviors are observed in a story about an American visiting her Frenchman-wed sister in Paris.

Actors : Alessandro Nivola, Abigail Breslin, Brittany Snow, Elisabeth Shue,
Directors : David M. Rosenthal,

A young girl who has been abandoned by her former-groupie mother informs a fading rock star that she is his daughter.

Actors : Bob Papenbrook, David Lodge, Joshua Seth, Lara Jill Miller,

Three different stories involving digital creatures collide together.

Actors : Dinara Drukarova, Nino Khomasuridze, Temur Kalandadze, Esther Gorintin,
Directors : Julie Bertuccelli,

The one joy in the lives of a mother and daughter comes from the regular letters sent to them from Paris from the family's adored son, Otar. When the daughter finds out that Otar has died ...

Actors : Nick Cannon, Forest Whitaker, Kim Basinger, Kelsey Grammer,
Directors : Mark Rydell,

Gambling addiction bring the stories of three otherwise unconnected people together as it destroys each of their lives.

Actors : James Frain, Ashley Judd, Stockard Channing, Natalie Portman,
Directors : Matt Williams,

A pregnant 17-year-old rebuilds her life after being abandoned by her boyfriend at a Wal-Mart in Sequoyah, Oklahoma.

Actors : Marina de Van, Thibault de Montalembert, Léa Drucker, Laurent Lucas,
Directors : Marina de Van,

A woman grows increasingly fascinated with her body after suffering a disfiguring accident.

Actors : Samantha Morton, Anthony John Crane, Gina St. John, Ron King,
Directors : Cecilia Miniucchi,

A turbulent and intriguing love story between two parking officers in the city of Los Angeles.

Actors : Marina Cacciotti, Maria Calì, Grazia Cesarini Sforza, Valeria De Franciscis,
Directors : Gianni Di Gregorio,

Gianni is a middle-aged man living in Rome with his imposing and demanding elderly mother. His only outlet from her and the increasing debt into which they are sinking, are the increasingly...

Actors : Juliette Lewis, Jennifer Lopez, Billy Campbell, Tessa Allen,
Directors : Michael Apted,

After running away fails, a terrified woman (Jennifer Lopez) empowers herself in order to battle her abusive husband (Billy Campbell).

Actors : Lucy Tulugarjuk, Fiona Gordon, Dominique Abel, Philippe Martz,

Fiona, Julien and their two clone-like children live a life appropriate to the robots they have become, in a style-less, cheerless suburb somewhere in the flatlands of French-speaking ...

Actors : Scott Cohen, Lisa Kudrow, Natalie Portman, Charlie Tahan,
Directors : Don Roos,

The story of a woman dealing with her daughter's death while trying to keep her marriage and her relationship with her stepson.

Actors : Isabelle Adjani, Grégori Derangère, Virginie Ledoyen, Gérard Depardieu,
Directors : Jean-Paul Rappeneau,

An actress, a writer, a student, and a government worker band together in an effort to escape Paris as the Nazis move into the city.