Best Female Lead movies of 2000s

Actors : Sonequa Martin-Green, Samantha Eustace, Louisa Krause, Maha Chehlaoui,
Directors : Emily Abt,

A story about two lacrosse teammates from opposite sides of the track.

Actors : Silvio Muccino, Adalberto Maria Merli, Liam Cunningham, Stefania Rocca,
Directors : Dario Argento,

A Rome policewoman teams up with a British Interpol agent to find a crafty serial killer whom plays a taunting game of cat-and-mouse with the police by abducting and killing young women and showing it over an Internet web cam.

Actors : Cara Seymour, Gary Farmer, Noah Fleiss, Mary Kay Place,
Directors : Enid Zentelis,

A young girl seduced by a boy's affluent, seemingly idyllic family, goes to extremes to gain acceptance and escape her poverty-stricken homelife.

Actors : Catherine Zeta-Jones, Justin Bartha, Andrew Cherry, Kelly Gould,
Directors : Bart Freundlich,

In New York City, a single mom captivates her new neighbor, a much younger man.

Actors : Katharine Isabelle, Brendan Fletcher, Emily Perkins, Tatiana Maslany,
Directors : Brett Sullivan,

Ginger's sister Brigitte, now a werewolf herself, must try to find a cure for her blood lust before the next full moon while hiding out in a rehab clinic from a relentless werewolf.

Actors : Mathieu Demy, Émilie Dequenne, Michel Blanc, Catherine Deneuve,
Directors : André Téchiné,

A drama centered on a young woman who claims she was the target of an anti-Semetic attack and the subsequent media sensation it creates.

Actors : Paul Rudd, Saoirse Ronan, Tracey Ullman, Michelle Pfeiffer,
Directors : Amy Heckerling,

A mother falls for a younger man while her daughter falls in love for the first time. Mother Nature messes with their fates.

Actors : Adriano Giannini, Bruce Greenwood, Elizabeth Banks, Madonna,
Directors : Guy Ritchie,

A snooty socialite is stranded on a Mediterranean island with a communist sailor.

Actors : Niklaus Lange, Susan May Pratt, Ali Hillis, Richard Speight Jr.,
Directors : Hans Horn,

When a group of friends fail to lower the ladder of their boat, they find themselves stranded in the surrounding waters and struggle to survive.

Actors : Stephen Brian Jones, Andrew Thaman, Charles Socarides, Elisabeth Moss,
Directors : Deborah Kampmeier,

When a teenager finds herself pregnant, with no memory of having had sex, she determines that she is carrying the child of God.

Actors : Tiffany Shepis, Luciano Szafir, Aaron Sherry, Blythe Metz,
Directors : Rolfe Kanefsky,

After receiving an African fertility mask as a gift Ellen tells her husband William that she's been attacked by masked phantom called 'the Nightmare Man'. As Ellen's paranoia increases, ...

Actors : Sami Bouajila, Stéphanie Lagarde, Nathalie Baye, Audrey Tautou,
Directors : Pierre Salvadori,

A hairdresser forwards a passionate love letter to her mother.

Actors : Elisabeth Harnois, Jesse McCartney, Margo Harshman, Ignacio Serricchio,
Directors : Todd Kessler,

Natalie has it all: yearbook editor, scholarship to college, star athlete, reigning social queen. Then Keith enters her life. Secretive and enigmatic, he slowly lures her from her comfort ...

Actors : Sarah Michelle Gellar, Sigourney Weaver, George Carlin, Patrick Warburton,

An alliance of evil-doers, led by Frieda, looks to take over Fairy Tale Land. But when Ella realizes her stepmother is out to ruin her storybook existence, she takes a dramatic turn and blossoms into the leader of the resistance effort.

Actors : Selma Blair, O'Neal Compton, Max Beesley, Lochlyn Munro,
Directors : Dana Lustig,

Shawn Holloway has a miserable life since she was eleven, when her father left her mother and she stayed alone with her problematic mother. Presently she is graduated, works in a bank and ...

Actors : Nicholas Gleaves, Michelle Williams, Ewan McGregor, Matthew Macfadyen,
Directors : Sharon Maguire,

A woman's life is forever changed when tragedy strikes at a soccer match.

Actors : Jean-Paul Roussillon, Frédéric Pierrot, Michel Serrault, Mathilde Seigner,
Directors : Christian Carion,

Sandrine, a woman in her thirties gets tired of life in Paris and decides to leave her work in computers and become a farmer. She takes the required practice for two years, and after that ...

Actors : Michael Biehn, Jesse Bradford, Brittany Murphy, Jay Mohr,
Directors : Geoffrey Wright,

In the small town of Cherry Falls, a psychotic murderer is killing off the virgins of the local high school.

Actors : Chizuru Ikewaki, Yoshihiko Hakamada, Takayuki Yamada, Aki Maeda,
Directors : Hiroyuki Morita,

After helping a cat, a young girl finds herself involuntarily engaged to a cat prince in a magical world where her only hope of freedom lies with a dapper cat statuette come to life.

Actors : Columbus Short, Tom Skerritt, Kate Beckinsale, Gabriel Macht,
Directors : Dominic Sena,

U.S. Marshal Carrie Stetko tracks a killer in Antarctica, as the sun is about to set for six months.