Best Female Lead movies of 2000s

Actors : Eugene Levy, Mary-Kate Olsen, Andy Richter, Ashley Olsen,
Directors : Dennie Gordon,

One day in New York City, as Jane Ryan tries out for an overseas college program and her sister Roxy schemes to meet her favorite punk rockers, a series of mishaps throws their day into ...

Actors : Ken Jeong, Bradley Cooper, Sandra Bullock, Thomas Haden Church,
Directors : Phil Traill,

Convinced that a CCN cameraman is her true love, an eccentric crossword puzzler trails him as he travels all over the country, hoping to convince him that they belong together.

Actors : Hilary Swank, Christopher Eccleston, Ewan McGregor, Richard Gere,
Directors : Mira Nair,

A look at the life of legendary American pilot Amelia Earhart, who disappeared while flying over the Pacific Ocean in 1937 in an attempt to make a flight around the world.

Actors : Angelina Jolie, Tony Shalhoub, Christian Kane, Edward Burns,
Directors : Stephen Herek,

A reporter interviews a psychic, who tells her that she's going to die and her life is meaningless.

Actors : Jessica Paré, Jackie Burroughs, Piper Perabo, Mischa Barton,
Directors : Léa Pool,

A newcomer to a posh girls boarding school discovers that her two senior roommates are lovers.

Actors : Leonor Watling, Rosario Flores, Javier Cámara, Darío Grandinetti,
Directors : Pedro Almodóvar,

Two men share an odd friendship while they care for two women who are both in deep comas.

Actors : Lindsay Lohan, Glenne Headly, Adam Garcia, Megan Fox,
Directors : Sara Sugarman,

A teenage girl is convinced that her home city revolves around her until her family packs up and moves to the suburbs, where she finds herself competing for attention.

Actors : John Krasinski, Adam Brody, Anna Faris, Roscoe Lee Browne,
Directors : Gregg Araki,

After a young actress unknowingly eats her roommate's marijuana cupcakes, her day becomes a series of misadventures.

Actors : Ludivine Sagnier, Chiara Mastroianni, Clotilde Hesme, Louis Garrel,
Directors : Christophe Honoré,

A musical interpretation of three lovers living in Paris.

Actors : Charlyne Yi, Jake Johnson, Gill Summers, Michael Cera,
Directors : Nicholas Jasenovec,

Charlyne Yi embarks on a quest across America to make a documentary about the one subject she doesn't fully understand: Love.

Actors : Michèle Caucheteux, Jean-Claude Donda, Michel Robin, Monica Viegas,
Directors : Sylvain Chomet,

When her grandson is kidnapped during the Tour de France, Madame Souza and her beloved pooch Bruno team up with the Belleville Sisters--an aged song-and-dance team from the days of Fred Astaire--to rescue him.

Actors : Lake Bell, Paul Rudd, Jason Biggs, Eva Longoria,
Directors : Jeff Lowell,

A ghost tries to sabotage her former boyfriend's current relationship with a psychic.

Actors : Brittany Murphy, Holly Hunter, Kathy Bates, Ron Livingston,
Directors : Nick Hurran,

A woman snoops through her boyfriend's palm pilot and reveals his former girlfriends, which causes her to question why they're still listed in his little black book.

Actors : Ian McShane, Renée Zellweger, Bradley Cooper, Jodelle Ferland,
Directors : Christian Alvart,

A social worker fights to save a girl from her abusive parents, only to discover that the situation is more dangerous than she ever expected.

Actors : Rachel Nichols, Wes Bentley, Simon Reynolds, Philip Akin,
Directors : Franck Khalfoun,

A businesswoman is pursued by a psychopath after being locked in a parking garage on Christmas Eve.

Actors : Tom Wilkinson, Helen Hunt, Scarlett Johansson, Milena Vukotic,
Directors : Mike Barker,

While retaining her secret identity, the illustrious Mrs. Erlynne (Hunt) saves Lady Windemere (Johansson) from making a grand social faux-pas with the scoundrelly Lord Darlington (Moore).

Actors : Chieko Baishô, Takuya Kimura, Tatsuya Gashûin, Akihiro Miwa,
Directors : Hayao Miyazaki,

When an unconfident young woman is cursed with an old body by a spiteful witch, her only chance of breaking the spell lies with a self-indulgent yet insecure young wizard and his companions in his legged, walking castle.

Actors : Salma Hayek, Jeanne Tripplehorn, Xander Berkeley, Stellan Skarsgård,
Directors : Mike Figgis,

Four frames of simultaneous action that alternately follow a smitten lesbian lover as she obsesses over her partner's dalliances and the tense goings-on of a Hollywood film production company.

Actors : Skandar Keynes, Georgie Henley, William Moseley, Tilda Swinton,
Directors : Andrew Adamson,

Four kids travel through a wardrobe to the land of Narnia and learn of their destiny to free it with the guidance of a mystical lion.

Actors : Patricia Clarkson, Alexander Siddig, Elena Anaya, Amina Annabi,
Directors : Ruba Nadda,

A romantic drama about a brief, unexpected love affair that catches two people completely off-guard.