Best Female Lead movies of 2000s

Actors : Jennifer Baxter, Dennis Hopper, Vin Diesel, Barry Pepper,

The wannabe sons of mobsters go to a remote town in the Midwest, and get themselves into more trouble than anyone could anticipate.

Actors : Abigail Breslin, Julia Ormond, Stanley Tucci, Joan Cusack,
Directors : Patricia Rozema,

Set in Cincinnati at the height of the Great Depression, Kit Kittredge, a resourceful young girl, helps her mother run a boardinghouse after her father loses his job.

Actors : Juno Temple, Eva Green, Imogen Poots, María Valverde,
Directors : Jordan Scott,

A look at the lives and relationships among girls at an elite boarding school.

Actors : Patricia Clarkson, Alexander Siddig, Elena Anaya, Amina Annabi,
Directors : Ruba Nadda,

A romantic drama about a brief, unexpected love affair that catches two people completely off-guard.

Actors : Lindsay Lohan, Dermot Mulroney, Felicity Huffman, Jane Fonda,
Directors : Garry Marshall,

A troubled young woman is sent to live with her grandmother for the summer, while hiding a secret that could potentially tear her family apart.

Actors : Melissa George, Mena Suvari, Marla Sokoloff, Marley Shelton,
Directors : Francine McDougall,

A popular high-school cheerleader becomes pregnant by the star quarterback and turns to crime to support her desired lifestyle.

Actors : Robert Englund, Jenna Jameson, Roxy Saint, Penny Vital,
Directors : Jay Lee,

A zombie epidemic spreads throughout a strip club in Nebraska.

Actors : Romola Garai, Bill Nighy, Sophie Stuckey, Rose Byrne,
Directors : Tim Fywell,

A love story set in 1930s England that follows 17-year-old Cassandra Mortmain, and the fortunes of her eccentric family, struggling to survive in a decaying English castle.

Actors : Andrew Howard, Daniel Franzese, Sarah Butler, Jeff Branson,
Directors : Steven R. Monroe,

A writer who is brutalized during her cabin retreat seeks revenge on her attackers, who left her for dead.

Actors : Nia Vardalos, Toni Collette, David Duchovny, Stephen Spinella,
Directors : Michael Lembeck,

A mob mix-up in Chicago sends two chanteuses screaming for L.A., where they score a perfect gig: posing as drag queens on the dinner theater/cabaret circuit. Things get extra-weird when a guy falls for one of the girls.

Actors : Will Arnett, Amy Poehler, Moises Arias, Bridgit Mendler,
Directors : Hiromasa Yonebayashi,

The Clock family are four-inch-tall people who live anonymously in another family's residence, borrowing simple items to make their home. Life changes for the Clocks when their daughter, Arrietty, is discovered.

Actors : James Fleet, Cate Blanchett, Abigail Cruttenden, Charlotte McDougall,
Directors : Gillian Armstrong,

A young Scottish woman joins the French Resistance during World War II to rescue her Royal Air Force boyfriend who is lost in France.

Actors : Holland Taylor, Mick Weber, Vincent D'Onofrio, Marisa Tomei,
Directors : Brad Anderson,

Ruby Weaver has man trouble: she tries to fix them, so she's stuck herself with a string of losers. Her current lover, Sam Deed, seems different: he's sweet, tender, just in from Dubuque. ...

Actors : Emmanuelle Devos, Geoffrey Carey, Thierry Bosc, Olivier Rabourdin,
Directors : Arnaud Desplechin,

Parallel storylines tell the current state of affairs for two ex-lovers: Nora's a single mother who comes to care for her terminally ill father; holed in up in mental ward, Ismael, a brilliant musician, plots his escape.

Actors : Parker Posey, John Ventimiglia, Kyra Sedgwick, Fairuza Balk,
Directors : Rebecca Miller,

Three women's escapes from their afflicted lives. Each struggles to flee from the men who confine their personal freedom.

Actors : Nicole Kidman, Christopher Eccleston, Fionnula Flanagan, Alakina Mann,
Directors : Alejandro Amenábar,

A woman who lives in a darkened old house with her two photosensitive children becomes convinced that her family home is haunted.

Actors : Steve Harris, Tyler Perry, Cicely Tyson, Kimberly Elise,
Directors : Darren Grant,

A couple's seemingly solid marriage begins to crumble when the wife discovers that her husband intends to divorce her.

Actors : Jacques Dutronc, Anna Mouglalis, Rodolphe Pauly, Isabelle Huppert,
Directors : Claude Chabrol,

In Lausanne, the aspirant pianist Jeanne Pollet has lunch with her mother Louise Pollet, her boyfriend Axel and his mother. Lenna leans that when she was born, a nurse had mistakenly told ...

Actors : Javier Cámara, Tim Robbins, Sverre Anker Ousdal, Sarah Polley,
Directors : Isabel Coixet,

A hearing impaired factory worker gives up her first holiday in years and instead travels out to an oil rig, where she cares for a man suffering from severe burns.

Actors : Sabine Azéma, Laura Morante, Pierre Arditi, Isabelle Carré,
Directors : Alain Resnais,

In Paris, six people all look for love, despite typically having their romantic aspirations dashed at every turn.